Monday, 17 September 2012

An Acceptable Risk...?

During the last visit to my diabetic clinic, I was asked to consider a new medication known as 'Victoza'. It is administered using an injection pen, once daily and it is known to work very well at lowering blood sugar levels and is also helpful in controlling weight.
I had for a long time been against any form of regular injection to help control my diabetes, viewing it as failure on my part. Having read the booklet I was given, it wasn't long before I was accepting the need for something more effective and seeing as I would need to inject just once a day, the idea began to gain favour with me.
As with all medication, I do like to do some research on the Internet to find out more about the tablets I take. I am particularly interested in finding out about how medicines are used in other countries and whether any adverse health risks resulting from taking them have been identified.


I have researched Victoza or Liraglutide as it is more commonly known and I have found a lot of information from various sources about its effectiveness in controlling blood sugar levels in Type 2 diabetics. This is good, but I have also found an alarming amount relating to the risk associated with thyroid cancer. It turns out that during tests on animals, an increase in the instances of thyroid cancers was detected. As a result, the medication in the US carries a 'Black Box' warning of the possible risk to humans of developing thyroid cancer. It is pointed out that the risk to humans has not been proved as no testing has been carried out and the medication hasn't been in use long enough for the results to be known. The FDA have however demanded that a 15 year study is undertaken amongst users of Victoza to detect any recorded increase in thyroid cancers.


Now, I worry about the slightest things, so you can imagine how this has me feeling at the moment. My relief at having been recommended a new medication to control my increasing blood sugar levels has now been replaced with a fear that, if the diabetes doesn't get me then thyroid cancer will. I know it sounds ridiculous but how much faith should I place in something that hasn't been properly tested? Should I take the medication knowing the risk, as the benefits outweigh the probability? It's very likely that should I develop thyroid cancers later on in life, no link would be made to my use of Victoza, and those that prescribed it would be long gone anyway, absolving themselves of any responsibility or blame.
I'm rather worried that when I visit my GP, he will claim to have no knowledge of the reported risks, and will look at me blankly when I raise it with him. He has done this before and it frustrates me immensely that I seem to be the only one prepared to do any research and to find out all I can about the tablets I put in me. I fear that the information I have discovered will again be dismissed as just rumour and speculation, but I am determined this time to press the point that a risk has been identified and that takers of Victoza are in effect live guinea pigs.
If I do consent to take the medication then I will insist that I am regularly tested for any abnormalities. I believe this is mandatory practise in other countries where Victoza has been approved, so it should be here in the UK.
Am I worrying needlessly? Most probably, but whilst there is sufficient concern, enough to warrant a FDA warning in the US then I can't help but be concerned.

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